The first noble truth is actually amazingly relatable for the most part, as in no reasonable person could find fault with it. Since it doesn't appear to have been mentioned, I will post a full literal translation of the first noble truth from the Dhammacakkappavattanasutta:
jātipi dukkhā Birth is dukkha
jarāpi dukkhā Old age is dukkha
byādhipi dukkho Sickness is dukkha
maraṇampi dukkhaṃ Death is dukkha
appiyehi sampayogo dukkho Association with the disliked is dukkha
piyehi vippayogo dukkho Separation from the beloved is dukkha
yampicchaṃ na labhati tampi dukkhaṃ Not obtaining one's wishes is dukkha
—saṃkhittena pañcupādānakkhandhā dukkhā. In brief, the five clinging aggregates are dukkha
People have a tendency to focus overly much on the final one, which is terribly difficult to translate into english, it can be explained but can't be rendered in a pithy way which does justice to the meaning. Putting aside that which is difficult to translate, the rest of it is very straightforward, and are about the actual physical and emotional sufferings in life we can all relate to.
These points are easily understood at a conceptual level, and make an excellent starting point of investigation. For example with the emotional pain of "being separated from the loved", I noticed I would experience a piercing pain the chest in association with being rejected by someone I loved, and I would note that that person was not in fact stabbing me in the chest and that therefore the painful feeling warranted serious investigation since it did not make sense.
It should be noted that the first noble truth does not make irrational statements such as "Association with the beloved is suffering", although we can notemay reason that being separated from the loved is inevitable and so that kind of pleasure is like a honeyed barb, it is pleasant at first, but will cut us later. Nevertheless the first noble truth does not deny the reality of that pleasure.