It is necessary to develop insight in the way ignorance lies at the basis for the conditioning of suffering. See 12 links of dependent co-origination. Insight in the conditioning of suffering is developed by seeing the four noble truths at work at every aspect of the dependent co-origination. Ie: fabrications are suffering because these will "colour" experience, therefore ending the fabrications (unskilful actions, complex emotions, fixed ideas,etc...) is to be achieved by developing wisdom instead of ignorance, and finally this transforming of ignorance into wisdom becomes the path of transformation. When then does the newly acquired skill itself become redundant and a hindrance to liberation?
Somehow the thinking part, the studying element of the development of wisdom creates a structure essential to gain insight into suffering. This knowledge may then become a kind of established truth, again giving rise to clinging to it, craving for it, ... and ultimately the birth of "the truth". This doctrine now needs to be defended, is liable to decay and misinterpretation, ... in short suffering. As it is impossible to use the insight to overcome itself (this is like a vicious circle), the only option left is to know when to abandon the knowledge (like in the raft simile) lest it becomes anew a cause for suffering. I hope this does clarify the issue somewhat.