Light is movement of photons which vibrate within a certain frequency range and travel at the speed of light. If there there is no one present with eyes to sense light, is there still light? I would say yes.
Nibbana is a permanent phenomena (dhamma) which is like light. Even if there are no enlightened ones to experience it, it is still there.
From MN 49 with corrected translation from this answer:
That which could be known (Nibbana), is invisible, infinite, radiant
all round—that’s what is not within the scope of experience based on
earth, water, fire, air, creatures, gods, the Creator, Brahmā, the
gods of streaming radiance, the gods replete with glory, the gods of
abundant fruit, the Overlord, and the all.
Also Ud 8.1-4.
But wisdom (panna) is different. It depends on the mind. If the mind ceases, then wisdom ceases. When the Buddha passed away, his wisdom ceased, but his teachings (Dhamma) which arose out of his wisdom, continue to exist through the suttas and the noble sangha.
So are the teachings (Dhamma) permanent or unconditioned? I would say no. If the suttas and the noble sangha disappear after many centuries or millennia (i.e. the end of the current Buddha sasana), then the teachings also disappear.
Some have asked if physical space is permanent or unconditioned. From Einstein's theory of general relativity, we know that physical space-time is conditioned.
So, in every case, we can see that only one phenomena is permanent and unconditioned and that is Nibbana. It is that which is experienced by the mind when it is free of defilements and fetters. It is not a mental idea or state of mind or state of consciousness.